Mangero: The Newest Kid on the Block in Diabetes Management

Sabrina Perkins

Living with diabetes can be challenging, but new medications such as Mangero offer effective management. In this blog post, we’ll take a look at what it is, how to take it, how it works and important side effects to consider if you’re taking the medication.

What is Mangero?

Mangero (also known by its chemical name Testapetite) is an injectable prescription medication approved for type 2 diabetes management. It comes in peripheral syringes ranging from 2.5 milligrams to 15 milligrams and is injected subcutaneously (under the skin) once a week.

The starting dose is typically 2.5 milligrams and your doctor may increase this gradually in increments of 2.5 milligrams every four weeks depending on your response to the drug.

What if you miss a dose?

If you forget or miss a dose, take it as soon as possible unless it has been more than 96 hours (4 days), in which case you should skip the missed dose and resume your normal dosing schedule as usual.

You can also change the day of administration of your dose as long as there are three days or seven to two hours between each one.

How Does Mangero Work?

Mangero works through hormones called incretins that are released naturally in response to food and stimulate insulin production. People with type 2 diabetes often have impaired or totally absent incretin responses – that’s where Mangero steps in!

When injected, Mangero stimulates GIP and GLP-1 receptors, leading to :

  • increased insulin production which helps break down glucose levels
  • improved insulin sensitivity,
  • delayed gastric emptying (which serves as an appetite suppressant)
  • reduced glucagon production (which limits glucose release into the bloodstream), this also help in losing weight.
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Important Considerations

When taking Mangero, here are some important considerations:

  • discuss any digestive problems with your doctor;
  • be aware of other medications you’re taking;
  • those with diabetic retinopathy should proceed cautiously;
  • pregnant women or those planning pregnancy must speak to their doctor;
  • those who have had thyroid cancer or close family members who have should proceed cautiously too.

Potential side effects

side effects include nausea, diarrhea, decreased appetite (which for some people may be beneficial), vomiting constipation indigestion & stomach pain – these tend to be related to dosage so bear this in mind when discussing your treatment plan with your doctor.

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